国产精品区一 I 欧美xxxx做受视频 I 亚洲中文字幕人成乱码 I 小早川怜子xxxxaⅴ在线 I 亚洲一区欧美激情 I 黄色免费观看网址 I 91成人小视频 I 日韩在线视频观看 I 强迫大乳人妻中文字幕 I 桃花久久 I 久久天天躁夜夜躁狠狠躁 I 精品人妻伦一二三区久久aaa片 I 日韩亚洲欧美视频 I 欧美国产精品久久久 I 亚洲女人天堂 I 亚洲免费性 I 在线观看国产精品普通话对白精品 I av大秀 I 91av综合 I 两个人看的www视频免费完整版 I 51自拍视频 I 911亚洲精品第一 I 日本美女毛片 I 午夜亚洲福利在线老司机 I 亚洲精品成人av I 亚洲精品无码久久久久av麻豆 I 欧美一级片网站 I 特黄熟妇丰满人妻无码 I 黄色片xxx I 日本熟妇xxxx潮喷视频

【Indications】

Acute and chronic diarrhea caused by acute non-specific infection, intestinal flora imbalance caused by antibiotics, chronic liver disease and other reasons, and related acute and chronic diarrhea and dyspepsia.

【R&D and Commercial Production of CLOBICO】

In 1996, Clostridium butyricum and Bifidobacterium infantis were screened and obtained;

In 1997, the strains were deposited in the China General Microbiological Culture Collection Center;

In 1999, the clinical trial approval was obtained, and the phase I, II and III clinical trials were initiated;

In 2001, the new drug certificate was obtained;

In 2002, the production approval was obtained;

In 2008, the stability study of cold-chain transportation under intermittent ambient temperature was carried out;

In 2009, the filing of intermittent temperature during cold-chain transportation was completed, and the package insert was noted that "in case of intermittent refrigeration temperature during transportation, the shelf life should not exceed 7 days, and light and heat should be avoided".

In 2010, a multicenter randomized controlled clinical trial of Combined Clostridium Butyricum and Bifidobacterium Powder in the prevention of antibiotic-associated diarrhea in children with pneumonia was carried out, and the results confirmed that: Combined Clostridium Butyricum and Bifidobacterium Powder could effectively reduce the risk of AAD in hospitalized children with pneumonia, and the incidence of AAD in the test group was 7.8% (13/193) within 7 days of observation;